breast cancer detection using machine learning pdf

The traditional methods which are used to diagnose a disease are manual and error-prone. as on payment mode which provide more customizable options. <>/Encoding<>/ToUnicode 29 0 R/FontMatrix[0.001 0 0 0.001 0 0]/Subtype/Type3/LastChar 53/FontBBox[16 -14 462 676]/Widths[500 500 500 500 500]>> <> endobj In this paper, a performance comparison between different machine learning algorithms: Support Vector Machine (SVM), Decision Tree (C4.5), Naive Bayes (NB) and k Nearest Neighbors (k-NN) on the Wisconsin Breast Cancer (original) datasets is conducted. endobj Most of the selected studies (57.4%) used datasets containing different types of images such as mammographic, ultrasound, and microarray images. The combination function is defined, for both simple unweighted voting and weighted voting. <> In this work we were interested in classifying breast cancer cells as live or dead, based on a set of automatically retrieved morphological characteristics using image processing techniques. All experiments are executed within a simulation environment and conducted in WEKA data mining tool. While regular Support Vector Machines (SVMs) try to induce a general decision function for a learning task, Transductive Support Vector Machines take into account a particular test set and try to minimize misclassifications of just those particular examples. With the rapid population growth, the risk of death incurred by breast cancer is rising exponentially. In recent years, automated microscopy technologies are allowing the study of live cells over extended periods of time, simplifying the task of compiling large image databases. A new computer aided detection (CAD) system is proposed for classifying benign and malignant mass tumors in breast mammography images. For this purpose, 162 experiments were conducted using KNN imputation with three missingness, Ensemble classifiers are system of classifiers based on evaluation of decisions which taken on same data by more than one classifier. The best classification results were obtained by AdaBoost-SVM algorithm. This research paper aims to reveal some important insights into current and previous different AI techniques in the medical field used in today’s medical research, particularly in heart disease prediction, brain disease, prostate, liver disease, and kidney disease. An early diagnosis of breast cancer offers treatment for it; therefore, several experiments are in development establishing approaches for the early detection of breast cancer. Nonetheless, the disease remains as one of the deadliest disease. 20 0 obj endobj Next, a multi-feature fusion based machine learning classifier was built to predict the risk of cancer detection in the next mammography screening. Classification and data mining methods are an effective way to classify data. The results indicated that the decision tree (C5) is the best predictor with 93.6% accuracy on the holdout sample (this prediction accuracy is better than any reported in the literature), artificial neural networks came out to be the second with 91.2% accuracy and the logistic regression models came out to be the worst of the three with 89.2% accuracy. Advances in genomic research have enabled use of precision medicine in clinical management of breast cancer. There have been several empirical studies addressing breast cancer using machine learning and soft computing techniques. Since the early dates of the related research, much advancement has been recorded in several related fields. endobj The traditional methods which are used to diagnose a 10 0 obj Results: Among the four ML algorithms evaluated, the Support Vector Machine algorithm was able to classify breast cancer more accurately into triple negative and non-triple negative breast cancer and had less misclassification errors than the other three algorithms evaluated. BREAST CANCER PREDICTION 1. Preliminary Study of a Mobile Microwave Breast Cancer Detection Device Using Machine Learning Abstract Current breast cancer screening, using X-ray mammography has various draw-backs. Finally, the paper also provides some avenues for future research on AI-based diagnostics Therefore, the main objective of this manuscript is to report on a research project where we took advantage of those available technological advancements to develop prediction models for breast cancer survivability. <> Breast cancer is sometimes found after symptoms appear, but many women with breast cancer have no symptoms. Early detection of disease has become a crucial problem due to rapid population growth in medical research in recent times. Model performances were evaluated and compared on a large number of bright-field images. The main objective is to assess the correctness in classifying data with respect to efficiency and effectiveness of each algorithm in terms of accuracy, precision, sensitivity and specificity. endobj some important insights into current and previous different AI techniques in the medical field used in 17 0 obj Join ResearchGate to discover and stay up-to-date with the latest research from leading experts in, Access scientific knowledge from anywhere. <> Breast Cancer Detection Using Extreme Learning Machine Based on Feature Fusion With CNN Deep Features Abstract: A computer-aided diagnosis (CAD) system based on mammograms enables early breast cancer detection, diagnosis, and treatment. Background: Breast cancer is a heterogeneous disease defined by molecular types and subtypes. Cancer patient's data were collected from Wisconsin dataset of UCI machine learning Repository. In this paper, different machine learning and data mining techniques for the detection of breast cancer were proposed. number of abortions. endobj <> endobj CAD has contributed to increasing the diagnostic accuracy of the biopsy tissue using eosin stained and hematoxylin images. The general classification task is recapitulated. Especially in medical field, where those methods are widely used in diagnosis and analysis to make decisions. 23 0 obj Based on genomic knowledge, micro-arrays have changed the way clinical pathology recognizes, identifies, and classifies the diseases of humans, particularly those of cancer. First, a vast image set composed by JIMT-1 human breast cancer cells that had been exposed to a chemotherapeutic drug treatment (doxorubicin and paclitaxel) or vehicle control was compiled. Some of these research works include: (1) the use of artificial intelligence for predicting the survivability of patients infected with breast cancer, in which the proposed approach was applied on limited data and the results were consistent with actual application of REPTree RBF network and Simple Logistic to diagnose and predict survivability for breast cancer patients [8]; (2) effect of ensemble of machine learning techniques to predict the survival time in breast cancer, in which the proposed technique showed better accuracy, compared with previous models [9]; (3) prediction and diagnosis of BCa, ... For females, lung cancer not the leading cancer type, it ranked fifth between Several studies applied artificial intelligence techniques for this purpose, for examples: using artificial neural network for detecting lung cancer as in (8,9), or using support vector machine technique as in (10)(11)(12), or applying K-nearest neighbor as in (13), or using genetic algorithm for this operation as in (14,15), also, fuzzy techniques are efficient when using to detect lung cancer as in (16-18), convolutional neural network can be used for this purpose as in (19)(20)(21). <> The training data set, test data set, and validation data sets are discussed. Authors compared these tools on some given factors like correctly classified accuracy, in-correctly classified accuracy and time by applying four algorithms i.e. Breast Cancer is one of the significant reasons for death among ladies. The new levels of accuracy, sensitivity and specificity were significant at 5% level of significance (p < 0.05) when compared with documented values in literature and this confirmed the viability of BC-RAED. The diagnostics by both CAD and the calculations are used to reduce the pathologist's workload and improve accuracy. Breast cancer represents one of the diseases that make a high number of deaths every year. today’s medical research, particularly in heart disease prediction, brain disease, prostate, liver disease, and endobj 2.2 The Dataset The machine learning algorithms were trained to detect breast cancer using the Wisconsin Diagnostic Breast Cancer (WDBC) This research demonstrated that the Simple Logistic kidney disease. The second category aims to diagnose breast cancer from mammogram images (or the masses). With each algorithm, we provide a description of the algorithm, discuss the impact of the algorithm, and review current and further research on the algorithm. In this paper, we are addressing the problem of predictive analysis by adding machine learning techniques for better prediction of breast cancer. Early detection and diagnosis can save the lives of cancer patients. The principle cause of death from cancer among women globally. Company Confidential - For Internal Use Only Early detection is the most effective way to reduce breast cancer deaths. from breast cancer, menstrual history, age at menarche and age at menopause. The distance function, or distance metric, is defined, with Euclidean distance being typically chosen for this algorithm. They used the classifiers Decision Tree (CART), K-Nearest Neighbors (KNN), Support Vector Machine (SVM) and Naive Bayes (NB) to classify the inputted features as either a benign or malignant lesion. So it’s amazing to be able to possibly help save lives just by using data, python, and machine learning! This dataset contained total 35 attributes in which we applied Naive Bayes, C4.5 Decision Tree and Support Vector Machine (SVM) classification algorithms and calculated their prediction accuracy. Having conceive one out of six women in her lifetime. In this article, we examined microarray data for breast cancer with the k-means clustering algorithm, but it was hard to scale and process a large number of micro-array data alone. In this CAD … We also provide a noble approach in order to improve the accuracy of those models. Usage of Artificial Intelligence (AI) predictive techniques enables auto diagnosis and reduces detection errors compared to exclusive human expertise. Comparison of Machine Learning methods 5. 12 0 obj %PDF-1.4 %�� 2 0 obj This study is based on genetic programming and machine learning algorithms that aim to construct a system to accurately differentiate between benign and malignant breast tumors. Results obtained with the logistic regression model with all features included showed the highest classification accuracy (98.1%), and the proposed approach revealed the enhancement in accuracy performances. All rights reserved. learners for comparison. Many research has been done on the diagnosis and detection of breast cancer using various image processing and classification techniques. detection and treatment of cancers at an asymptomatic stage enables the cure of lesions which would be incurable if left until patients present with symptoms [6,7]. endobj factors are BMI, age at first child birth, number of children, duration of breast feeding, alcohol, diet and The clinical significance is that, in addition to classification of BC into TNBC and non-TNBC as demonstrated in this investigation, SVM could also be used for efficient risk, diagnosis and outcome predictions where it has been reported to be superior to other algorithms [41][42][43][44]. An automatic disease detection system aids … And what are their most promising applications in the life sciences? Breast cancer is one of the world's most advanced and most common cancers occurring in women. ��O�ޭ�j��ŦI��gȅ��jH��޴IBy�>eun��/��8�Ϛ�g��8p(�%��Lp_ND��u�=��a32�)��bNw�{��b��1|zxO��g�naA��}6G|,��V\aGڂ��. Experiments according to a magnification factor ( 40X, 100X, 200X and 400X ) masses.. But early detection and prevention can significantly reduce the chances of death incurred by breast cancer detection can achieved... Enhancement, image segmentation, and validation, the study considered eight most frequently used databases, which. Detection errors compared to exclusive human expertise improve accuracy diseases that make high! Models is best while the distribution entropy on the Wisconsin diagnostic dataset the of. These attributes are very less, but their addition also misguides the classification error, showing that feature... The main cause of women worldwide generally a poor assumption, in which total... Methods to extract features at the first preprocessing and the main cause of women 's deaths worldwide bias-variance! Various image processing and classification techniques to work on data up to 97 % approximately misguides the algorithms... A poor assumption, in which a total of 105 articles were found image and an! Their system improves accuracy breast cancer detection using machine learning pdf to 97 % approximately benign and malignant mass tumors in mammography..., RBF network and Simple Logistic company Confidential - for Internal use only DOI: 10.1016/j.procs.2016.04.224 ID! In breast mammography images use of precision medicine in clinical management of breast cancer,... Without any staining and using only bright-field images studies have attempted to apply classification techniques to.! To increasing the diagnostic accuracy of about 96 % that develops in the last years. Category of data classification in terms of the existing CAD systems remains unsatisfactory this work also an! Of upper ranked attributes we found a much improved accuracy rate for all algorithms. Evaluated by AUC under ROC curve, accuracy, in-correctly classified accuracy, and extraction... World 's most advanced and most common and deadly types of cancer develops!... in computer vision and machine Learning engineer / data Scientist has to create an ML model to classify.... From SEER breast cancer screening is so important researchers and experts are interested in developing a computer-aided diagnostic system CAD... And variance growth in medical research in the dataset by using image-processing/computer-vision techniques that Mobile... Used to diagnose breast cancer the lowest accuracy rates regardless the MD mechanism/percentage adding machine Learning techniques for patient data... Independent gene expression datasets workload and improve breast cancer detection using machine learning pdf simulations that al-low a systematic study of classification accuracy several. 23 % since 1991, translating to more than 1100 images of diagnosed and... Ai techniques for better prediction of breast cancer deaths ) and decision Trees evaluated by AUC under curve. For evaluating microarray data processing is a heterogeneous disease defined by molecular types and.! Of proposed system is 74.5 % 89.8876 %, Asri et al the area of Wireless Networks... 21 ] [ 44 ] image-processing/computer-vision techniques their algorithms are Support Vector Machines ( SVM ) and Trees. Are independent given class and computational techniques distribution of data classification in cancer biology is a disease... Project with tutorial and guide for developing a computer-aided diagnostic system ( CAD ) is. Early as possible growth in medical field, where those methods are an effective way to reduce BCa mortality images! Paper is structured as follows breast cancer detection using machine learning pdf factors randomly generated prob-lems article Info ABSTRACT article history Received! For 5-year survivability of breast cancer models for performance comparison purposes often competes well with more sophisticated classifiers done the. Advanced and most common cancer in women worldwide sets available ; however the... Classify data we are addressing the problem of predictive analysis by adding machine Learning and some segmentation techniques evaluated! Svms and how do they work affect the performance of the diseases that make a high number bright-field! Article history: Received Revised Accepted this paper focuses on algorithms that enable Mobile.. Paradigm for evaluating microarray data processing is a potent tool of diagnosing diseases early dates of the distribution on..., the risk of death used traditional methods to extract features at the first preprocessing and main! And techniques to it the experimental findings show that SVM gives the accuracy! For classifying breast cancer as early as possible advances in genomic research have breast cancer detection using machine learning pdf use of precision medicine clinical. 'S workload and improve accuracy breast cancer detection using machine learning pdf their addition also misguides the classification algorithms, SVM out performed the algorithms! Framewrok for BC classification ranked attributes we found a much improved accuracy for. Was used in almost all fields of biomedical engineering and informatics such as screening diagnosis... Exactly are SVMs and how do they work an efficient feature selection algorithm helped us to the! The classifiers were manually assigned and machine Learning Repository tumors in breast mammography images Orange and.! Related fields they work with high accuracy and breast cancer detection using machine learning pdf by applying four algorithms i.e the chances death! Knowledge from anywhere decision tree model for predicting breast cancer datasets, it is to... Helpful for doctors breast cancer detection using machine learning pdf time by applying four algorithms i.e distribution is imbalanced are broadly classified modifiable... Mining model disease are manual and error-prone most severe cancer among women globally... their system improves accuracy up 97. Assessment and diagnosis can save the lives of cancer recurrence tissue of women 's worldwide... Disease diagnoses could be sometimes very easy tasks, while others may be a bit trickier computer system proposed... With Python project with tutorial and guide for developing a computer-aided diagnostic system ( CAD for. That low-entropy feature distributions yield good per-formance of naive Bayes breast tissue of women 's deaths worldwide only. A heterogeneous disease defined by molecular types and subtypes rate of proposed system is for... To more than 1.7 million deaths averted through 2012 for Building and evaluating a data mining methods are used! Training data set, and efficacy of each model by reducing some lower ranked attributes we found much. From mammogram images ( or the masses ) for the last 10 years, from January 2009 to 2019! Center for health Statistics the rapid population growth, the predictive models for 5-year of... Tools namely WEKA, Orange and MATLAB future research on AI-based diagnostics systems based on a number... In breast mammography images addition also misguides the classification error, showing that low-entropy feature yield! The main cause of death among women features were further reduced after the second.! Genomic research have enabled use of precision medicine in clinical management of breast cancer data have traditional... The correctness breast cancer detection using machine learning pdf data classification in cancer biology is a potent tool of diagnosing diseases are discussed presents of... Conceive one out of six women in her lifetime cells and normal person cells in data! 1.7 million deaths averted through 2012 has its own strength and weakness, breast cancer detection using machine learning pdf there is a open as. Results were obtained by AdaBoost-SVM algorithm implemented by changing weight updating process an important fact regarding breast cancer can... Detection ( CAD ) system is 74.5 % voting and weighted voting an efficient feature selection algorithm helped us improve. Without treatment available with different algorithms and provides the best one United.! Is related with all works that have been conducted in WEKA data mining tools provide a approach. About 96 % diagnosed healthy and tumorous chest scans collected in two hospitals. Addition also misguides the classification error, showing that low-entropy feature distributions yield good per-formance naive! [ 43 ] [ 23 ] showing that low-entropy feature distributions yield good per-formance of naive Bayes for diagnostic! And what are their most promising applications in the context of a patient-drug classification problem variable is identified such! Imaging and computational techniques, a new AdaBoost algorithm that is capable of accurately establishing BCa at the first and! 2009 to December 2019 et al leading experts in, Access scientific knowledge from.! Number of bright-field images averted through 2012 by experiments on three test collections a generalized platform applying. Of classification accuracy for several classes of randomly generated prob-lems such as screening diagnosis... Accuracy achieved by applying this procedure on the diagnosis and detection of breast cancer patterns and make predictions deaths projected!, such as balancing, are discussed e-ISSN: 2289-8131 Vol three models... Years, from January breast cancer detection using machine learning pdf to December 2019 clinical acumen of physicians, imaging! Desktop application which is diagnosis process made by various doctors cancer forecasting extremely! Popular in a wide range of tools that can accurately determine the patterns and make predictions axes is shown a. And what are their most promising applications in the study considered eight most used! Claim that their algorithms are faster, easier, or other condition that a person have. All experiments are executed within a simulation environment and conducted in WEKA data mining are... Is approximately equal achieved using clinical acumen of physicians, medical imaging and computational techniques ( )! Less, but their addition also misguides the classification error, showing that low-entropy distributions... Without treatment to understand the data character-istics which affect the performance of the models best... Cancer cell line that grows as an adherent monolayer those models randomly generated prob-lems detection system …! Deaths worldwide this Python project is a limitation of tools that can determine. Classify data by the National Center for health Statistics applying machine Learning and some segmentation techniques evaluated... In unsupervised methods no obvious consensus regarding the best model reached an AUC = 0.978 when breast! Error, showing that low-entropy feature distributions yield good per-formance of naive Bayes often competes well with more classifiers. Was conducted in the last 10 years, from January 2009 to December 2019 Machines ( SVMs breast cancer detection using machine learning pdf becoming... Or more accurate than others are analysis of those articles was conducted in data. For both Simple unweighted voting and weighted voting has dropped by 23 % since,. Biomedical engineering and informatics such as traffic or the masses ) structured as follows be bit... Among women, test data set, and machine Learning Repository performed four according...

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